BioSempra NAD+ supplement bottle on a white background

NAD+ 500 mg - with Quercetin & Resveratrol

Name: NAD+ 500 mg - with Quercetin & Resveratrol
Rating: 4.61 (36 reviews)

NAD+ levels fall with age. This formula delivers 500 mg of NAD+ alongside quercetin and resveratrol, supporting the cellular energy and metabolic function behind a demanding day.*

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Your cells run on NAD+. It's the coenzyme behind cellular energy production and metabolic function, and your levels fall as you age. Each serving of BioSempra NAD+ delivers 500 mg of NAD+ (Nicotinamide Adenine Dinucleotide) to support normal cellular function and everyday vitality, paired with 250 mg quercetin and 150 mg Japanese knotweed extract, the natural source of resveratrol. Three actives, every amount listed, no proprietary blend.

Quercetin is a naturally occurring plant flavonoid that provides antioxidant support and supports immune function. Resveratrol, sourced from Japanese knotweed, supports cardiovascular health. Alongside NAD+, both help support energy and normal cellular function.

Made for adults who want to hold onto their energy and normal metabolic function through demanding days.

Supplement facts label with serving size, servings per container, and ingredient list for BioSempra NAD+.

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If for any reason you're not satisfied with your order, you can return the product for a full refund or store credit, whichever you prefer.

Third-Party Testing

All BioSempra supplements are third-party tested. We also only work with GMP Certified & FDA registered facilities in the USA to ensure you get a premium quality supplement.

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Benefits of Daily Use

Consistency matters with a longevity supplement. Here's what a daily routine supports.

Support cellular energy - NAD+ is central to how your cells produce energy.*

Antioxidant support from two directions - Quercetin and resveratrol work alongside NAD+.*

Invest in the long game - Supports normal cellular function as you age.*

Frequently Asked Questions

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell of the body, playing a central role in cellular energy production and metabolic function. NAD+ levels naturally decline with age, which is why supporting them has become a focus for people interested in longevity.*

Research suggests that NAD+ levels can drop as we age, as the body's consumption of NAD+ increases. This decline is associated with reduced cellular energy production.*

NAD+ is the active coenzyme your cells use directly, while NMN is a precursor that your body converts into NAD+. An NAD+ supplement provides the coenzyme itself, which your body breaks down during digestion and rebuilds inside your cells through its natural pathways, whereas NMN feeds that production pathway one step earlier. Both are valid approaches and are often used together as part of a longevity-focused routine.*

Our NAD+ Supplement combines 500 mg of NAD+ with quercetin and resveratrol, two plant-based compounds that complement NAD+'s role in cellular function. Rather than offering a single-active product, this formula is designed to support cellular energy, antioxidant defenses, and cardiovascular health from multiple angles.*

We recommend taking two capsules daily in the morning with 6 oz of water. Many people prefer mornings as an easy habit to keep. What matters most is taking it consistently at the same time each day.

5 stars: 23 (64%)
4 stars: 12 (33%)
3 stars: 1 (3%)
2 stars: 0 (0%)
1 star: 0 (0%)

Small capsules that are easy to take. I feel i have more energy after taking this supplement for 4 weeks now

No side effects. I feel amazing every morning

A great anti aging supplement. I like that they have 3rd pary testing

Good ingredient list on this supplement that i bought.

Helps with brain health

Good quality

i switched from nmn to direct nad+ because i wanted something more direct. the energy boost is immediate, but i find i need to space it out to avoid feeling over-stimulated in the evening. overall, i feel sharper

5/5 stars

Noticeably quicker recovery now

i’m a night shift worker, so my circadian rhythm is often off. since starting nad+, my sleep-wake cycle has stabilized. i fall asleep faster and wake up feeling refreshed, even after working nights.

After trying various nootropics, nad+ stands out. It supports cellular repair. I feel like i’m maintaining my health better than my peers

Very good

i live in a cold climate, and i usually feel sluggish in winter. this year, despite the cold and dark, my energy levels remained high. nad+ is the only thing that changed in my routine, and it’s made a huge difference

I compared this to a cheaper nad+ brand, and the difference is palpable. The cheaper one made me feel slightly bloated; this one is smooth and effective. I can definitely tell the difference in my endurance during runs

I am happy that i bought from here

I take 500mg of nad+ daily. I’ve noticed that my cognitive function during high-stress workdays is much more resilient. I don’t get that "wired but tired" feeling in the evenings anymore.

Direct nad+ is pricey, but worth it

love that the pills are not too big,

BioSempra is trustworthy

No crash at all from this.

I like it.

Sleep has been much better recently

best nad+ supplement.

Better than NMN for me.

Great

Helps with focus

no jitters.

Recommended by my doctor

i take nad+ before bed. it doesn’t keep me awake, but i wake up feeling more refreshed and less groggy than usual. it seems to help regulate my energy levels throughout the next day.

i’m 60 years old and have joint pain. my doctor suggested nad+ infusions, but i started with oral supplements to see if it would help. after two months, my joint stiffness is noticeably less, and i have more energy for daily walks.

I use nad+ to help with alcohol recovery. it helps replenish my body’s stores faster. i wake up less sluggish and feel more balanced the next day. it’s become a staple in my weekend routine